Low-level laser or LED photobiomodulation on oral mucositis in pediatric patients under high doses of methotrexate: prospective, randomized, controlled trial
Guimarães DM, Ota TMN, da Silva DAC, et al.
Supportive Care in Cancer · 2021
- Study type
- Prospective randomized controlled trial
- Population
- Pediatric patients receiving high-dose methotrexate
- Source access
- Abstract & publisher link
A prospective randomized study comparing laser and LED approaches for oral mucositis in a defined pediatric cancer-care setting.
What to keep in mind
The participants were receiving high-dose methotrexate under oncology care. A comparison of specific oral PBM approaches does not establish safety across devices or indications, nor does it establish transcranial safety. This research is not a home-treatment protocol.
Research information is not a prescription. Long-term pediatric transcranial PBM safety is not established by these studies; adult evidence is not a substitute for pediatric evidence. Use only under qualified clinical guidance, with device-specific safety review.
Read the abstract & publisher linkThe original publication opens at its journal or research repository. Full text availability depends on the source; articles have not been copied or rehosted.